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上海奥尔科特生物科技有限公司是研发、设计、制造科学实验仪器与系统设备的专业企业,自1992年起致力于研发和生产生命科学实验系统与设备,产品广泛应用,为祖国的科学研究事业做出了贡献。
奥尔科特公司产品为中国科学院、中国医学科学院、军事医学科学院、北京大学、清华大学、复旦大学、上海交通大学、香港大学、阿斯利康、药明康德等院校与企业采用。
奥尔科特公司产品被选用在国家高新技术研究发展项目、国家973计划项目、国家863计划项目、国家与军队重大计划项目等各种重要科学研究,涵盖医学、药物研发、化学、物理、生物、运动、心理、工业等领域。

在实验研究中使用奥尔科特的产品,近年发表的部分科学研究论著
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Extract of Plantago asiatica L. seeds ameliorates hypertension in spontaneously hypertensive rats by inhibition of angiotensin converting enzyme. Frontiers Pharmacology,30 April2019
Local upregulation of interleukin-1 beta in aortic dissecting aneurysm: correlation with matrix metalloproteinase-2, 9 expression and biomechanical decrease. Interactive CardioVascular and Thoracic Surgery, Volume 28, Issue 3, March 2019, Pages 344–352
Correlation of cardiomyocyte apoptosis with duration of hypertension, severity of hypertension and caspase 3 expression in hypertensive rats. Experimental and Therapeutic Medicine, 2019,Volume17,Issue 4
TLR2 and TLR4 mediate an activation of adipose tissue renin-angiotensin system induced by uric acid, Biochimie, Volume 162, July 2019, Pages 125-133
Protective effect of Xin-Ji-Er-Kang on cardiovascular remodeling in high-salt induced hypertensive mice: Role ofoxidative stress and endothelial dysfunction, Biomedicine & Pharmacotherapy,Volume 115, July 2019, 108937
Dexmedetomidine ameliorates post-CPB lung injury in rats by activating the PI3K/Akt pathway, Journal of Investigative Surgery, 2019,26 Mar 2019
Regulatory T Cells Could Improve Intestinal Barrier Dysfunction in Heatstroke,Inflammation,01 March 2019
Ivabradine improved left ventricular function and pressure overload-induced cardiomyocyte apoptosis in a transverse aortic constriction mouse model, Molecular and cellular biochemistry,January 2019,Volume450,Issue1-2,p25-34
The Dual Neuroprotective-Neurotoxic Effects of Sevoflurane After Hemorrhage Shock Injury, Journal of Surgical Research, 2019 - Volume 235, March 2019, Pages 591-599
Transthoracic Pulmonary Artery Denervation for Pulmonary Arterial Hypertension: Sympathetic Nerve Distribution and Pulmonary Artery Remodeling,Arteriosclerosis, Thrombosis, and Vascular Biology. 2019;39:704–718
Paeoniflorin improves pressure overload-induced cardiac remodeling by modulating the MAPK signaling pathway in spontaneously hypertensive rats, Biomedicine & Pharmacotherapy, Volume 111, March 2019, Pages 695-704
Implantation of engineered conduction tissue in the rat heart,Molecular medicine reports 2019,February5, 2019,Pages2687-2697
Sevoflurane postconditioning protects against myocardial ischemia/reperfusion injury by restoring autophagic flux via an NO-dependent mechanism,Acta Pharmacologica Sinicavolume 40,pages35-45,2019
Acute immune responses are involved in liver and kidney injury in heat stroke,European Journal of Inflammation, April 4, 2019
Effect of olprinone on ischemia-reperfusion induced myocardial injury in rats, Biomedicine & Pharmacotherapy, Volume 111, March 2019, Pages 1005-1012
Repair of Peripheral Nerve Sensory Impairments via the Transplantation of Bone Marrow Neural Tissue-Committed Stem Cell-Derived Sensory Neurons,Cellular and Molecular Neurobiology,April 2019, Volume 39, Issue 3, pp 341-353
ZIPK mediates endothelial cell contraction through myosin light chain phosphorylation and is required for ischemic-reperfusion injury, The FASEB Journal, 10 Jun 2019
Protective effect of Xin Ji Er Kang on cardiovascular remodeling in high salt induced hypertensive mice, Experimental and Therapeutic Medicine, 2019 Volume17 Issue3
Angiotensin-converting enzyme 2 in the rostral ventrolateral medulla regulates cholinergic signaling and cardiovascular and sympathetic responses in hypertensive, Neuroscience bulletin, February 2019, Volume 35, Issue 1, pp 67–78
Total Salvianolic Acid Injection Prevents Ischemia/Reperfusion-Induced Myocardial Injury Via Antioxidant Mechanism Involving Mitochondrial Respiratory, Shock: June 2019,Volume51,Issue6, p745-756
Localized injection of miRNA-21-enriched extracellular vesicles effectively restores cardiac function after myocardial infarction, Theranostics.2019; 9(8): 2346-2360
Chemerin stimulates aortic smooth muscle cell proliferation and migration via activation of autophagy in VSMCs of metabolic hypertension rats, Am J Transl Res 2019;11(3):1327-1342
Crocin attenuation of neurological deficits in a mouse model of intracerebral hemorrhage,Brain Research Bulletin,Volume 150, August 2019, Pages 186-195
Xuezhikang improves the outcomes of cardiopulmonary resuscitation in rats by suppressing the inflammation response through TLR4/NF-κB pathway, Biomedicine & Pharmacotherapy,Volume 114, June 2019, 108817
Activation of nicotinic acetylcholine α7 receptor attenuates progression of monocrotaline-induced pulmonary hypertension in Rats by downregulating the NLRP3, Front.Pharmacol., 26 February 2019
Extract of Plantago asiatica L.seeds ameliorates hypertension in spontaneously hypertensive rats by inhibition of angiotensin converting enzyme, Frontiers in Pharmacology 2019
Effect of isoflurane on myocardial ischemia-reperfusion injury through the p38 MAPK signaling pathway, European Review for Medical and Pharmacological Sciences,2019; 23: 1342-1349
Phenylbutyrate Ameliorates Anxiety Disorder by Inhibiting Endoplasmic Reticulum Stress after Diffuse Axonal Injury, Journal of NeurotraumaVol. 36,No.11,2019
The protective effects of polysaccharide extract from Xin-Ji-Er-Kang formula on Ang II-induced HUVECs injury, L-NAME-induced hypertension and cardiovascular remodeling in mice, BMC Complementary and Alternative Medicine 2019,19:127
Modification of T cells function after restoration of spontaneous circulation in a rat model of cardiac arrest, BioRxiv, 2019 February25, 2019
Royal jelly causes hypotension and vasodilation induced by increasing nitric oxide production, Food Science & Nutrition,Volume7, Issue4, April 2019,Pages 1361-1370
The TLR-4/NF-κB signaling pathway activation in cochlear inflammation of rats with noise-induced hearing loss, Hearing Research, Volume 379, August2019,Pages59-68
The Relationship between Hematoma Expansion Induced by Hypertension and Hyperglycemia and Blood-Brain Barrier Disruption and Its Possible Mechanism:Role of Aquaporin-4 and Connexin43,June5,2019
Using co-axial electrospray deposition to eliminate burst release of simvastatin from microparticles and to enhance induced steogenesis,Journal of Biomaterials Science, Polymer Edition Volume 30, 2019 Issue 5
Protective Effects of 18β-Glycyrrhetinic Acid on Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats, Front. Pharmacol., 22 January 2019
N-Acetyl Serotonin Protects Neural Progenitor Cells Against Oxidative Stress-Induced Apoptosis and Improves Neurogenesis in Adult Mouse Hippocampus Following, Journal of Molecular Neuroscience April 2019, Volume 67, Issue 4, pp 574–588
Identification of RyR2-PBmice and the effects of transposon insertional mutagenesis of the RyR2 gene on cardiac function in mice, PeerJ Biochemistry, Biophysics and Molecular Biology section, 2019
NADPH oxidase 1/4 inhibition attenuates the portal hypertensive syndrome via modulation of mesenteric angiogenesis and arterial hyporeactivity in rats, Clinics and Research in Hepatology and Gastroenterology Volume 43, Issue 3, June 2019, Pages 255-265
CPI-17-mediated contraction of vascular smooth muscle is essential for the development of hypertension in obese mice,Journal of Genetics and Genomics,Volume46, Issue3, 20 March 2019, Pages109-118
Ischemic duration and frequency determines AKI-to-CKD progression monitored by dynamic changes of tubular biomarkers in IRI mice, Front Physiol.2019;10:153.
Repetitive anodal transcranial direct current stimulation improves neurological outcome and survival in a ventricular fibrillation cardiac arrest rat model,Brain Stimulation,Volume12,Issue3, May-June 2019, Pages 659-667
An effective dendritic cell‐based vaccine containing glioma stem‐like cell lysate and CpG adjuvant for an orthotopic mouse model of glioma, Journal of Cancer,2019Volume144,Issue111 June 2019, Pages 2867-2879
Intravenous Transplants of Human Adipose-Derived Stem Cell Protect the Rat Brain From Ischemia-Induced Damage, Journal of Stroke and Cerebrovascular Diseases, Volume 28, Issue 3, March 2019, Pages 595-603
Effects of the combination of Herba Epimedii and Semen Plentaginis on the aortic ACE2/Angiotensin-(1-7)/Mas receptor axis and blood pressure in,Int J Clin Exp Med 2019;12(4):3376-3386
糖尿病大鼠罗库溴铵神经肌肉阻滞作用的药效学.中国医学科学院学报,2019,41(02):149-155.
消融Marshall韧带远段对急性心力衰竭犬心房颤动易感性的影响.中国心脏起搏与心电生理杂志,2019,33(02):138-143.
七氟醚对低温灌注大鼠离体心脏电生理稳定性的影响.中华麻醉学杂志,2019(04):440-442.
脑心通胶囊肠吸收液清除DPPH自由基的有效成分辨识研究.中国现代中药,2019,21(04):448-453.
益母草有效成分配伍抗大鼠心肌缺血再灌注损伤作用研究.中国医院药学杂志,2019,39(07):708-712.
TCONS_00016478通过PGC1-α/ PPARγ信号通路影响实验性房颤兔心房肌能量代谢重构的机制.山东大学学报(医学版),2019,57(04):1-8.
天麻钩藤汤对自发性高血压模型大鼠的疗效及其对血管壁氧化应激的干预作用.世界中医药,2019,14(03):593-597.
标本配穴对心肌缺血再灌注损伤糖尿病大鼠心肌细胞的影响及机制研究.北京中医药大学学报,2019,42(03):260-264.
阈下剂量钙拮抗剂对小鼠心肌缺血再灌注损伤作用研究.汕头大学医学院学报,2019,32(01):1-4.
t-PA基因修饰的内皮祖细胞对大鼠急性心肌梗死的治疗作用.中国动脉硬化杂志,2019,27(03):204-210.
电针“内关”预处理对心肌缺血再灌注损伤大鼠血清代谢物的影响.针刺研究,2019,44(03):176-182
低温联合右美托咪啶对兔心肌细胞缝隙连接蛋白43分布的影响.贵州医科大学学报,2019,44(03):289-292.
电针对大鼠颅脑损伤后认知功能的改善作用.山东中医杂志,2019,38(03):261-264
匹诺塞林在t-PA溶栓所致出血转化中的作用.药学学报,2019,54(03):448-453.
天龙通心片对心肌缺血再灌注损伤及血液流变学的影响.中国实验方剂学杂志,2019,25(10):41-47.
硫化氢对脓毒症大鼠膈肌功能障碍的保护作用.世界临床药物,2019,40(01):29-33.
注射用红花黄色素经TLR-NF-κB炎症通路抗大鼠MIRI的保护作用研究.中国中药杂志,2019,44(12):2566-2571.
次乌头碱和甘草苷及甘草次酸配伍对急性心力衰竭大鼠的动态保护研究.中华中医药杂志,2019,34(02):746-750.
电针、艾灸预处理对心肌缺血大鼠心肌细胞凋亡和自噬的影响.针刺研究,2019,44(01):31-36.
不同温度对离体大鼠心室肌单相动作电位、电兴奋性的影响.山东医药,2019,59(03):47-50.
丹酚酸A与阿司匹林抗血栓作用的比较研究.药学学报,2019,54(02):301-307.
代谢综合征合并心肌梗死大鼠模型的建立及氧化应激相关机制的探讨.天津医药,2019,47(01):26-31.
化瘀方抗大鼠心肌纤维化疗效及其与氧化应激的关系.重庆医学,2019,48(01):6-10.
骨髓间充质干细胞对心脏骤停后大鼠脑海马神经生长因子和Caspase-3表达的影响.中华急诊医学杂志,2019(01):30-34.
氢吗啡酮后处理对大鼠缺血-再灌注心律失常及心肌缝隙连接蛋白43表达的影响.医药导报,2019,38(01):9-13.
不同姜制附子对急性心力衰竭大鼠血流动力学的影响.中华中医药杂志,2019,34(01):332-335.
不同矿物成因禹余粮的止泻作用.中国实验方剂学杂志,2019,25(05):21-28.
脑心通胶囊肠吸收液保护过氧化氢致H9c2心肌细胞损伤的作用机制及有效药味筛选.中国实验方剂学杂志,2019,25(04):29-35.
向天果提取物对肾性高血压动物试验研究.动物医学进展,2019,40(01):69-73.

 

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