产品应用

上海奥尔科特生物科技有限公司是研发、设计、制造科学实验仪器与系统设备的专业企业,自1992年起致力于研发和生产生命科学实验系统与设备,产品广泛应用,为祖国的科学研究事业做出了贡献。
奥尔科特公司产品为中国科学院、中国医学科学院、军事医学科学院、北京大学、清华大学、复旦大学、上海交通大学、香港大学、阿斯利康、药明康德等院校与企业采用。
奥尔科特公司产品被选用在国家高新技术研究发展项目、国家973计划项目、国家863计划项目、国家与军队重大计划项目等各种重要科学研究,涵盖医学、药物研发、化学、物理、生物、运动、心理、工业等领域。

在实验研究中使用奥尔科特的产品,近年发表的部分科学研究论著
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N-acetylcysteine restores sevoflurane postconditioning cardioprotection against myocardial ischemia-reperfusion injury in diabetic rats. Journal of Diabetes Research2016 (6) :1-8
Protective effects of thoracic epidural anesthesia on hypoxia-induced acute lung injury in rabbits.Experimental & Therapeutic Medicine, 2016 , 11 (5) :2021
Amelioration of salvianolic acid C on aortic structure in apolipoprotein E-deficient mice treated with angiotension II. Life sciences, 2016
Advanced glycation end products inhibit distal colon contraction in rats via protein kinase C-dependent modulation of intracellular calcium.Int J Clin Exp Med 2016;9(9):18780-18789
Beneficial effects of dantrolene on sepsis-induced diaphragmatic dysfunction are associated with downregulation of high-mobility group box 1 and calpain-caspase-3.Journal of surgical research, 2016
Cardioprotective effects of combined therapy with hyperbaric oxygen and diltiazem pretreatment on myocardial ischemia-reperfusion injury in rats. Cellular Physiology & Biochemistry, 2016 , 38 (5) :2015-2029
Close concordance between pulmonary angiography and pathology in a canine model with chronic pulmonary thromboembolism and pathological mechanisms after lung ischemia reperfusion injury.Journal of Thrombosis & Thrombolysis, 2016 , 41 (4) :581
An injectable silk sericin hydrogel promotes cardiac functional recovery after ischemic myocardial infarction. Acta biomaterialia, 2016
Deactivation of Association Cortices Disrupted the Congruence of Visual and Auditory Receptive Fields in Superior Colliculus Neurons. Cerebral Cortex, 2016
Effect of stromal cell-derived factor-1 on myocardial apoptosis and cardiac function recovery in rats with acute myocardial infarction.Experimental and Therapeutic Medicine, 2016
Hypoxia-inducible factor-2α limits natural killer T cell cytotoxicity in renal ischemia/reperfusion injury. J Am Soc Nephrol. 2016 Jan;27(1):92-106
Endothelial dysfunction correlates with decompression bubbles in rats. Scientific Reports, 2016 , 6 :33390
Rescue of hypertension-related impairment of angiogenesis by therapeutic ultrasound. American Journal of Translational Research, 2016 , 8 (7) :3087
Astragaloside IV Attenuates Podocyte Apoptosis Mediated by Endoplasmic Reticulum Stress through Upregulating Sarco/Endoplasmic Reticulum Ca2-ATPase2 Expression in Diabetic Nephropathy. Frontiers in Pharmacology, 2016 , 7 :500
Overexcited MaxiK and KATP channels underlie obstructive jaundice-induced vasoconstrictor hyporeactivity of arterial smooth muscle. Scientific Reports, 2016 , 6 :39246
Synthesis and evaluation of novel angiotensin II receptor 1 antagonists as anti-hypertension drugs.Bioorganic & Medicinal Chemistry, 2016 , 24 (9) :2023-2031
Design, synthesis, and pharmacological evaluation of 5-oxo-1, 2, 4-oxadiazole derivatives as AT1 antagonists with antihypertension activities. Clinical & Experimental Hypertension, 2016 , 38 (5) :435
Functional nanoparticles activate a decellularized liver scaffold for blood detoxification. Small, 2016 , 12 (15) :2067
Antihypertensive activity of polysaccharide from Crassostrea gigas. International Journal of Biological Macromolecules 2016 , 83 :195
Effect of Salvia miltiorrhiza and ligustrazine injection on myocardial ischemia/reperfusion and hypoxia/reoxygenation injury. Molecular Medicine Reports, 2016 , 14 (5) :4537-4544
Sirtuin 1 activator SRT1720 protects against lung injury via reduction of type II alveolar epithelial cells apoptosis in emphysema. COPD: Journal of Chronic Obstructive Pulmonary Disease.Volume 12, 2015
Activation of the NLRP3 inflammasome induces vascular dysfunction in obese OLETF rats. Biochemical and Biophysical Research Communications.Volume 468, Issues 1–2, 4–11 December 2015, Pages 319–325
Long-Term Treatment of Clonidine, Atenolol, Amlodipine and Dihydrochlorothiazide, but Not Enalapril, Impairs the Sexual Function in Male Spontaneously .PLoS ONE10(1): 2015
Olmesartan restores the protective effect of remote ischemic perconditioning against myocardial ischemia/reperfusion injury in spontaneously hypertensive. Clinics, 2015
Early administration of cisatracurium attenuates sepsis-induced diaphragm dysfunction in rats.Inflammation, 2015
Protective effect of olmesartan against cardiac ischemia/reperfusion injury in spontaneously hypertensive rats. Experimental and Therapeutic Medicine 2015
骨内单次注射小剂量辛伐他汀对大鼠心梗后血管新生的影响.中国实验动物学报,2017,25(05):506-512.
冠心宁片对大鼠心肌缺血再灌注损伤的保护作用研究.中国比较医学杂志,2017,27(05):76-82.
人参总皂苷对心肌梗死后大鼠心功能和心室重构的影响.实用药物与临床,2017,20(05):497-501.
气血宁对心肌梗死大鼠心脏保护作用机制研究.北京中医药,2017,36(05):405-409
三七皂苷R_1对垂体后叶素致心肌缺血大鼠PK/PD的影响.今日药学,2017,27(06):375-379.
参附注射液抗早、中期心源性休克血流动力学指标的量效关系研究.时珍国医国药,2017,28(05):1247-1250.
甘氨酸偶联皮质醇抗Compound 48/80刺激大鼠急性过敏反应的作用研究.现代生物医学进展,2017,17(14):2611-2615
右美托咪定对大鼠心室肌电稳定性和缝隙连接蛋白43表达的影响:离体实验.中华麻醉学杂志,2017,37(05):577-580.
线粒体乳酸穿梭对小鼠主动脉弓缩窄术后心室重构和心力衰竭的影响.南京医科大学学报(自然科学版),2017,37(05):539-543.
前脑啡肽原基因转染对大鼠心肌缺血/再灌注损伤的影响.国际麻醉学与复苏杂志,2017,38(05):390-395.
内质网应激诱导的细胞凋亡在大鼠窒息性心跳骤停及复苏后脑损伤中的作用.中华神经医学杂志,2017,16(05):465-472.
PI3K/AKt/GSK3β信号通路在复苏中颈部降温的脑保护作用.中华急诊医学杂志,2017,26(05):554-559.
SP600125对蛛网膜下腔出血大鼠海马区神经细胞自噬及神经细胞丢失的影响.医学研究生学报,2017,30(05):470-475.
心跳骤停及复苏过程中脑损伤的程度及其机制.中华实验外科杂志,2017,34(05):807-810.
“太冲”配“内关”针刺对自发性高血压大鼠血压及延髓头端腹外侧区天冬氨酸及谷氨酸水平的影响.针刺研究,2017,42(02):102-106.
早期应用疏风清热合剂调节急性相蛋白和VEGF促进骨折愈合的实验研究.中国中西医结合杂志,2017,37(05):584-588.
针药结合对大鼠心肌缺血再灌注损伤影响实验研究.辽宁中医药大学学报,2017,19(07):57-59
电针内关穴预处理对心肌缺血再灌注损伤大鼠线粒体膜电位、腺苷A1受体的影响.湖南中医药大学学报,2017,37(04):402-405.
热习服对湿热环境运动刺激大鼠大脑皮质和心肌线粒体的影响.第二军医大学学报,2017,38(04):469-475.
MRI法评价氯胺酮对创伤性脑外伤小鼠的脑保护作用.中华麻醉学杂志,2017,37(04):501-503.
脓毒症大鼠通过降低肌浆网钙摄取和SERCA1表达损害膈肌舒张功能.南方医科大学学报,2017,37(04):438-443.
蛋白激酶CβⅡ (PKCβ2)抑制剂LY333531减少心肌梗死后心肌肥大细胞浸润.细胞与分子免疫学杂志,2017,33(04):517-520.
电针内关穴预处理对心肌缺血再灌注损伤大鼠NO、NOS及腺苷A1受体的影响.中国中医急症,2017,26(04):565-567+587.
杨桃根醇提物对正常大鼠血压的影响.华西药学杂志,2017,32(02):160-162.
加味四物汤水提物对急性心肌梗死小鼠骨髓细胞动员、定植及分化的影响.实用医学杂志,2017,33(07):1083-1086.
骨髓间充质干细胞移植修复心搏骤停后大鼠海马神经元损伤.中华急诊医学杂志,2017,26(04):405-409.
硫磺熏蒸对菊花入肠吸收成分影响.中国药学杂志,2017,52(07):553-559.
一种心脏立体电生理标测系统用于低强度迷走神经刺激术对在体大鼠心房颤动模型的研究.中国心脏起搏与心电生理杂志,2017,31(02):149-156.
杨桃果总黄酮对大鼠血压的影响.中华中医药杂志,2017,32(04):1786-1788.
两种大鼠心律失常模型的建立及比较.中国药理学通报,2017,33(04):591-592.

 

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