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上海奥尔科特生物科技有限公司是研发、设计、制造科学实验仪器与系统设备的专业企业,自1992年起致力于研发和生产生命科学实验系统与设备,产品广泛应用,为祖国的科学研究事业做出了贡献。
奥尔科特公司产品为中国科学院、中国医学科学院、军事医学科学院、北京大学、清华大学、复旦大学、上海交通大学、香港大学、阿斯利康、药明康德等院校与企业采用。
奥尔科特公司产品被选用在国家高新技术研究发展项目、国家973计划项目、国家863计划项目、国家与军队重大计划项目等各种重要科学研究,涵盖医学、药物研发、化学、物理、生物、运动、心理、工业等领域。

在实验研究中使用奥尔科特的产品,近年发表的部分科学研究论著
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Captopril alleviates hypertension-induced renal damage, inflammation, and NF-κB activation,Brazilian Journal of Medical and Biological Research, 2018,vol.51 no.11
Schisandrin attenuates lipopolysaccharide-induced lung injury by regulating TLR-4 and Akt/FoxO1 signaling pathways, Front.Physiol.,08 August 2018
Hydrogen Inhalation is Superior to Mild Hypothermia for Improving Neurological Outcome and Survival in a Cardiac Arrest Model of Spontaneously Hypertensive Rat, Shock,December2018,Volume50,Issue6,p689-695
Erythropoietin alleviates post-resuscitation myocardial dysfunction in rats potentially through increasing the expression of angiotensin II receptor type 2 in ,Molecular Medicine Reports,2018 Volume17 Issue4
Rat Brainstem Hemorrhage Model: Key Points to Success in Modeling, World Neurosurgery,Volume 117, September 2018, Pages e106-e116
Proteomic analysis reveals the renoprotective effect of Tribulus terrestris against obesity-related glomerulopathy in rats, Biological and Pharmaceutical Bulletin, 2018Vol.41, No9 p1430-1439
BAPTA-AM Nanoparticle for the Curing of Acute Kidney Injury Induced by Ischemia/Reperfusion, Journal of Biomedical Nanotechnology, Volume 14, Number5, May2018,p868-883(16)
Astragaloside IV prevents obesity-associated hypertension by improving pro-inflammatory reaction and leptin resistance, Mol Cells. 2018 Mar 31; 41(3): 244–255.
Protective effects of low tidal volume mechanical ventilation associated with WISP1-TRL4 signaling pathway in a sepsis model of mice, Int J Clin Exp Med 2018;11(8):7872-7884
Overexpression of Arrestin1 in the Rostral Ventrolateral Medulla Downregulates Angiotensin Receptor and Lowers Blood Pressure in Hypertension. Front.Physiol.,28 March 2018
Combining early post-resuscitation EEG and HRV features improves the prognostic performance in cardiac arrest model of rats, The American Journal of Emergency Medicine.Volume 36, Issue 12, December 2018, Pages 2242-2248
Betaine Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats via Inhibiting Inflammatory Response, Molecules 2018, 23(6), 1274
Topotecan alleviates ventilator-induced lung injury via NF-κB pathway inhibition Cytokine,Volume 110, October 2018, Pages 381-388
Comparison of quantitative characteristics of early post-resuscitation EEG between asphyxial and ventricular fibrillation cardiac arrest in rats, Neurocritical Care,April 2018, Volume 28, Issue 2, pp 247-256
Synergism of amlodipine and candesartan on blood pressure reduction and organ protection in hypertensive rats, Clinical and Experimental Pharmacology and Physiology, Volume45, Issue6,June 2018, Pages 514-524
Antihypertensive effects, molecular docking study, and isothermal titration calorimetry assay of angiotensin I-converting enzyme inhibitory peptides from Chlorella, Journal of agricultural, 2018
With a new clip technique surgically inducing varicocele in Sprague-Dawley rats, BMC Urology,201818:58
LPS ameliorates renal ischemia/reperfusion injury via Hsp27 up-regulation, International Urology and Nephrology,March 2018, Volume 50, Issue 3, pp 571-580
Effects of small interfering RNA targeting TLR4 on expressions of adipocytokines in obstructive sleep apnea hyponea syndrome with hypertension in a rat model, Journal of cellular Physiology 2018 Volume233, Issue10,Pages 6613-6620
Protective cerebrovascular effects of hydroxysafflor yellow A (HSYA) on ischemic stroke,European Journal of Pharmacology, Volume 818, 5 January 2018, Pages 604-609
A1AR-mediated renal protection against ischemia/reperfusion injury is dependent on HSP27 induction,International Urology and Nephrology, July 2018, Volume 50, Issue 7, pp 1355–1363
Spatial receptive field shift by preceding cross‐modal stimulation in the cat superior colliculus,The Journal of Physiology, Volume596, Issue2015 Pages 5033-5050, 2018
Exosomes derived from human umbilical cord mesenchymal stem cells improve myocardial repair via upregulation of Smad7, International Journal of Molecular Medicine,2018,Volume 41 Issue 5
Dihydromyricetin improves vascular hyporesponsiveness in experimental sepsis via attenuating the over-excited MaxiK and KATP channels, Pharmaceutical Biology Volume 56, 2018-Issue 1
Comparative Study of Ocular Pharmacokinetics of Gatifloxacin Between Continuous Lavage and Hourly Topical Instillation in Rabbits,November 2018 Volume37,Issue11,p1457-1462
Huangqi (astragalus) decoction ameliorates diabetic nephropathy via IRS1-PI3K-GLUT signaling pathway, American journal Translational Research. 2018;10(8):2491-2501.
The Metabolomics Study of the Shexiang Baoxin Pill, Systems Biology and its Application in TCM Formulas Research,2018,Pages229-253
Therapeutic effects of acupuncture treatment on experimental rats with intracerebral hemorrhage via promoting neovascularization, Int J Clin Exp Med 2018;11(12):13235-13242
ALDH2 Protects Against Ischemic Stroke in Rats by Facilitating 4-HNE Clearance and AQP4 Down-Regulation, Neurochemical Research, July 2018, Volume 43, Issue7, p1339-1347
Identification and characterization of circular RNAs in rapid atrial pacing dog atrial tissue, Biochemical and Biophysical Research Communications, Volume 506, Issue 1, 17 November 2018, Pages 1-6
Ivabradine promotes angiogenesis and reduces cardiac hypertrophy in mice with myocardial infarction, Anatolian journal of cardiology, 2018 Nov; 20(5): 266–272
Effects of gene knockdown of CNP on ventricular remodeling after myocardial ischemia-reperfusion injury through NPRB/Cgmp signaling pathway in rats, Journal of cellular Biochemistry, Volume119, Issue2,February 2018,Pages 1804-1818
MicroRNA-210 promotes angiogenesis in acute myocardial infarction. Molecular Medicine Reports, 2018 Volume17 Issue4
Effect of acupuncture at three different acupoints on electrical activity of gastric distention-affected neurons in rat medial vestibular nucleus.Journal of Traditional Chinese Medicine Volume 38, Issue 1, February 2018, Pages 125-131
Effect of Sini decoction on angiotensin II, transforming growth factor β1 and connective tissue growth factor in rats with myocardial fibrosis-induced banding of the abdominal aorta.Journal of Traditional Chinese Medicine Volume 38, Issue 3, June 2018, Pages 427-432
Total Flavone of Rhododendron Improves Cerebral Ischemia Injury by Activating Vascular TRPV4 to Induce Endothelium-Derived Hyperpolarizing Factor-Mediated Responses. Evidence-Based Complementary and Alternative Medicine Volume 2018,
Lithium posttreatment alleviates blood–brain barrier injury after intracerebral hemorrhage in rats, NeuroscienceVolume 383, 15 July 2018, Pages 129-137
A potential role of Baicalin to inhibit apoptosis and protect against acute liver and kidney injury in rat preeclampsia model, Biomedicine & Pharmacotherapy, Volume 108, December 2018, Pages 1546-1552
Protective effects of PI3KCG gene on acute myocardial infarction, Journal of thoracic disease,2018 Feb; 10(2): 941–953
TGF-β1 and connexin-43 expression in neurogenic bladder from rats with sacral spinal cord injury, Neurourology and urodynamics, 2018 Volume37, Issue8,ages 2502-2509
Pharmacological postconditioning with Neuregulin-1 mimics the cardioprotective effects of ischaemic postconditioning via ErbB4-dependent activation of reperfusion injury salvage kinase pathway, Molecular Medicine2018,24:39
Ursolic acid ameliorates oxidative stress, inflammation and fibrosis in diabetic cardiomyopathy rats, Biomedicine & Pharmacotherapy, Volume 97, January 2018, Pages 1461-1467
A preventive injection of endothelial progenitor cells prolongs lifespan in stroke-prone spontaneously hypertensive rats, Clinical Science Aug 30, 2018
The contribution of different components in qishenyiqi pills to its potential to modulate energy metabolism in protection of ischemic myocardial injury,Frontiers in Physiology., 11April2018
Abnormalities in the fiber composition and contractility in diabetic skeletal muscles, Int J Clin Exp Med 2018;11(2):753-763
Role of miR-34c in the cognitive function of epileptic rats induced by pentylenetetrazol,Molecular Medicine Report,January 17, 2018,Pages: 4173-4180
Metabolic syndrome emerges after artificial selection for low baroreflex sensitivity,CNS neuroscience & Therapeutics, Volume24, Issue9 September 2018,Pages 828-836
Effects of mTOR/NF-κB signaling pathway and high thoracic epidural anesthesia on myocardial ischemia‐reperfusion injury via autophagy in rats,Volume233, Issue9,2018, Pages 6669-6678
Effects of Xin-Ji-Er-Kang on Anticardiovascular Remodeling in L-NAME Induced Hypertensive Mice and Its Potential Mechanisms,Evidence-Based Complementary and Alternative Medicine,Volume 2018,
Gualou xiebai decoction, a traditional chinese medicine, prevents cardiac reperfusion injury of hyperlipidemia rat via energy modulation,Frontiers in Physiology,04 April 2018
The protective effects of distal ischemic treatment on apoptosis and mitochondrial permeability in the hippocampus after cardiopulmonary resuscitation,Journal of cellular Physiology, 2018, Volume233, Issue9 Pages 6902-6910
Trimetazidine protects against myocardial ischemia/reperfusion injury by inhibiting excessive autophagy, Journal of Molecular Medicine,August 2018, Volume 96, Issue 8, pp 791–806
Intracerebroventricular injection of Aβ1-42 combined with two-vessel occlusion accelerate Alzheimer's disease development in rats,Pathology - Research and Practice,Volume 214, Issue 10, October 2018, Pages 1583-1595
Role of glutamine in the mediation of E-cadherin, p120-catenin and inflammation in ventilator-induced lung injury, Chinese medical J (Engl). 2018 Apr 5; 131(7): 804–812
Soluble epoxide hydrolase inhibition with t-TUCB alleviates liver fibrosis and portal pressure in carbon tetrachloride-induced cirrhosis in rats, Clinics and Research in Hepatology and Gastroenterology,2018 Volume 42, Issue 2,Pages e23-e38, 99-174
Rapid delivery of Hsa-miR-590-3p using targeted exosomes to treat acute myocardial infarction through regulation of the cell cyclem, Journal of Biomedical Nanotechnology, 2018,Volume14, Number5
扶正化瘀胶囊对心肌梗死大鼠心肌纤维化及TGF-β_1/Smads信号通路的影响.中西医结合心脑血管病杂志,2018,16(09):1185-1189.
SK3表达在雌二醇介导的大鼠结肠平滑肌收缩中的作用.南京医科大学学报(自然科学版),2018,38(06):753-757+815.
心室颤动家兔QT变化与心肺复苏后恶性心律失常的关系.广西医科大学学报,2018,35(06):783-786.
人参总皂苷对大鼠急性心肌梗死模型血管新生及心功能的影响研究.中国畜牧兽医文摘,2018,34(06):120-121.
奥普力农调节自噬减轻大鼠心肌缺血-再灌注损伤.中华急诊医学杂志,2018,27(06):645-651.
生后不同间隔时间异氟烷处理对大鼠成年后认知功能的影响.解放军医学杂志,2018,43(06):465-471.
预防性应用辛伐他汀对大鼠脑出血后血肿体积和神经功能的影响.中国临床神经外科杂志,2018,23(05):331-334
无血预充大鼠体外循环模型的建立.中国体外循环杂志,2018,16(03):184-188
大鼠心肌梗死后血管内皮生长抑制因子的时程变化.南京医科大学学报(自然科学版),2018,38(05):612-615.
黄芪多糖对脓毒症大鼠心脏功能及炎症因子水平的影响.浙江中医药大学学报,2018,42(05):354-359.
改良经皮心外膜电刺激建立大鼠心脏骤停模型.中华急诊医学杂志,2018,27(05):513-517.
益气活血方对心肌梗死大鼠心肌纤维化影响的研究.环球中医药,2018,11(05):670-675.
厚朴对胃肠动力障碍作用的研究.中国医药导报,2018,15(13):31-34.
基于肠外翻-离体血管联用方法的银丹心脑通软胶囊血管活性评价.中华中医药杂志,2018,33(05):1724-1729.
白芍总苷对心肌缺血再灌注大鼠内质网应激因子CHOP、GRP78、GRP94的表达及凋亡的影响.现代生物医学进展,2018,18(08):1469-1473.
性别及去卵巢手术对肾血管性高血压大鼠左心室肥厚的影响.新疆医科大学学报,2018,41(04):403-407.
芳香新塔花总黄酮对大鼠心肌缺血再灌注损伤的保护作用及机制.中国实验方剂学杂志,2018,24(14):115-121
大鼠陈旧性心肌梗死中碎裂QRS波与心力衰竭的关系研究.中国临床保健杂志,2018,21(02):234-237.
肾血管性高血压大鼠血管和肾脏组织中RSA组分蛋白表达的性别差异性研究.新疆医科大学学报,2018,41(04):408-413.
桂枝甘草汤对心力衰竭大鼠心肌凋亡及心肌细胞TGF-β1、ICAM-1表达的影响.中华中医药学刊,2018,36(04):932-935
蛋白激酶C和酪氨酸激酶在机械通气相关肺损伤中的作用机制.中国医药,2018,13(04):537-540.
性别及年龄对原发性高血压大鼠炎症因子的影响.新疆医科大学学报,2018,41(04):399-402.
扶正化瘀胶囊对心肌梗死后心肌纤维化大鼠细胞外基质代谢的影响.中医杂志,2018,59(07):607-611.
柴胡龙骨牡蛎汤对心肌梗死大鼠骨髓c-kit~+干细胞动员的影响.北京中医药大学学报,2018,41(03):203-209.
妊娠对肺动脉高压肺循环影响的实验研究.心肺血管病杂志,2018,37(03):253-258.
性别对肾血管性高血压大鼠血压及靶器官损伤的影响.新疆医科大学学报,2018,41(04):389-393+398.
急性腹膜炎对大鼠罗库溴铵腹肌松弛和腹直肌功能的影响.上海医学,2018,41(03):139-144.
银杏内酯注射液对脑缺血再灌注小鼠炎症水平的影响.临床医药文献电子杂志,2018,5(76):1-5.
通心络对豚鼠肥厚心肌电压依赖性钾通道的影响.中华老年心脑血管病杂志,2018,20(09):977-980.
骨桥蛋白在大鼠重度创伤性脑损伤后肠黏膜中表达水平变化.创伤与急危重病医学,2018,6(05):263-266.
参附注射液灌胃对MIRI模型大鼠Ca~(2+)、KATP通道的影响.临床医学研究与实践,2018,3(26):5-6.
养阴润肠方改善慢传输型便秘模型ICC研究.中华中医药学刊,2018,36(09):2188-2191.
丝瓜络不同炮制品治疗功能失调性子宫出血的药效比较.山东中医杂志,2018,37(09):772-774.
17-甲氧基-7-羟基-苯骈呋喃查耳酮对小鼠心室肌细胞膜钠电流的影响.中国现代应用药学,2018,35(08):1185-1188.
神经调节蛋白1/表皮生长因子受体4信号通路的激活加强了七氟醚对心肌缺血/再灌注损伤大鼠的心肌保护作用.中国临床药理学杂志,2018,34(15):1843-1845.
滋阴潜阳方对2K1C高血压大鼠肾损伤的影响.光明中医,2018,33(15):2181-2184.
七氟烷对大鼠肺缺血再灌注损伤中ATM的影响.中国老年学杂志,2018,38(15):3756-3759.
甘松挥发油对大鼠心肌缺血再灌注损伤及磷脂酰肌醇3激酶通路的影响.实用临床医药杂志,2018,22(15):14-17.
通心络对肥大细胞介导的大鼠心肌I/R损伤中β-氨基己糖苷酶、类糜蛋白酶及蛋白激酶C表达的影响.环球中医药,2018,11(08):1191-1195.
制川乌不同煎煮时间对心衰大鼠血流动力学的影响.中国药师,2018,21(08):1343-1347.
基于网络药理学构建新型中药复方降压抗纤方抗高血压心肌纤维化的作用.中国实验方剂学杂志,2018,24(20):115-122.
慢性情绪应激对急性心肌梗死后骨髓c-kit~+干细胞动员的影响.中国循环杂志,2018,33(07):709-713.
鱼腥草挥发油对大鼠心肌缺血再灌注损伤的保护作用及机制研究.中南药学,2018,16(07):973-977.
PI3K/Akt信号通路在右美托咪定减轻体外循环大鼠肺缺血再灌注损伤的作用.中华麻醉学杂志,2018,38(07):803-807.
大鼠心肌缺血再灌注损伤模型线粒体自噬变化的研究.现代生物医学进展,2018,18(13):2452-2456.
黄芪甲苷联合依那普利治疗改善小鼠急性心肌梗死后心功能.南京医科大学学报(自然科学版),2018,38(07):945-949+1000.
基于TLR4/NF-κB通路探讨滋阴潜阳方对两肾一夹高血压大鼠肾损伤保护作用的机制.江西中医药大学学报,2018,30(05):82-85.
银杏内酯注射液对脑缺血再灌注损伤治疗时间窗及凋亡信号通路的影响.药物评价研究,2018,41(07):1169-1173.
高压氧预处理对大鼠脑出血后炎症反应的影响.健康研究,2018,38(03):294-297.
益气活血颗粒对心肌梗死大鼠尿液代谢组学的影响.北京中医药大学学报,2018,41(06):482-489.
依普利酮对糖尿病肾病大鼠的保护机制研究.中国现代应用药学,2018,35(06):812-815.
中药玉夏胶囊对自发性高血压大鼠肾纤维化的作用研究.中国临床药理学与治疗学,2018,23(06):632-639.
益气活血方对大鼠心肌梗死边缘区Sigma-1R、SERCA2a、IP3R mRNA表达的影响.中西医结合心脑血管病杂志,2018,16(09):1180-1184.

 

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