产品应用

上海奥尔科特生物科技有限公司是研发、设计、制造科学实验仪器与系统设备的专业企业,自1992年起致力于研发和生产生命科学实验系统与设备,产品广泛应用,为祖国的科学研究事业做出了贡献。
奥尔科特公司产品为中国科学院、中国医学科学院、军事医学科学院、北京大学、清华大学、复旦大学、上海交通大学、香港大学、阿斯利康、药明康德等院校与企业采用。
奥尔科特公司产品被选用在国家高新技术研究发展项目、国家973计划项目、国家863计划项目、国家与军队重大计划项目等各种重要科学研究,涵盖医学、药物研发、化学、物理、生物、运动、心理、工业等领域。

在实验研究中使用奥尔科特的产品,近年发表的部分科学研究论著
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Hepatic Hypoxia-Inducible Factors Inhibit PPARα Expression To Exacerbate Acetaminophen induced Oxidative Stress And Hepatotoxicity. Free Radical Biology 2017
The Cardiovascular Effect of Systemic Homocysteine Is Associated with Oxidative Stress in the Rostral Ventrolateral Medulla. Neural Plasticity, 2017
REM sleep deprivation induces endothelial dysfunction and hypertension in middle-aged rats: Roles of the eNOS/NO/cGMP pathway and supplementation with L-arginine. PloS one, 2017
Electroacupuncture improves acute bowel injury recovery in rat models. Experimental and Therapeutic Medicine 2017
The protective effects of electro-acupuncture in thoracic surgery on trauma stressed rats involve the rostral ventrolateral medulla and supraoptic nucleus. Brain Research Bulletin, 2017 , 134
Intrahepatic upregulation of MRTF-A signaling contributes to increased hepatic vascular resistance in cirrhotic rats with portal hypertension. Clinics & Research in Hepatology & Gastroenter , 2017 , 41 (3) :303
Relationship between the β1-adrenergic receptor and the β2-adrenergic receptor in hypertension.Int J Clin Exp Pathol, 2017
Enhancement in Tonically Active Glutamatergic Inputs to the Rostral Ventrolateral Medulla Contributes to Neuropathic Pain-Induced High Blood Pressure. Neural Plasticity, 2017
Dysfunction of the thymus in mice with hypertension. Experimental & Therapeutic Medicine, 2017 , 13 (4)
Study of Breath Acetone in a Rat Mode of 126 Rats with Type 1 Diabetes. Journal of Analytical & Bioanalytical Techniques, 2017 , 08 (1)
Effects of Gene Knockdown of CNP on Ventricular Remodeling after Myocardial Ischemia‐Reperfusion Injury through NPRB/Cgmp Signaling Pathway in Rats. Journal of Cellular Biochemistry, 2017
Altered mTOR and Beclin-1 mediated autophagic activation during right ventricular remodeling in monocrotaline-induced pulmonary hypertension. Respiratory Research, 2017 , 18 (1) :53
Renal sympathetic denervation raises blood pressure and attenuates ventricular remodeling in rats with myocardial infarction. Int J Clin Exp Med 2017;10(6):8884-8895
Modified lingguizhugan decoction incorporated with dietary restriction and exercise ameliorates hyperglycemia,hyperlipidemia and hypertension in a rat model of the metabolic syndrome.Bmc Complementary & Alternative Medicine, 2017 , 17 (1) :132
Beneficial Effects of Paeoniflorin Enriched Extract on Blood Pressure Variability and Target Organ Damage in Spontaneously Hypertensive Rats. Evid Based Complement Alternat Med. 2017
Protective effects of tanshinone IIA sodium sulfonate on ischemia-reperfusion-induced myocardial injury in rats. Iranian Journal of Basic Medical Sciences, 2017 , 20 (3) :308
Hydrogen sulfide prevents diaphragm weakness in cecal ligation puncture-induced sepsis by preservation of mitochondrial function. American Journal of Translational Research, 2017 , 9 (7) :3270
Differences in pharmacodynamic responses to rocuronium in normal or injured orbicularis oris are associated with expression of acetylcholine receptor subunits. Scientific Reports, 2017
Therapeutic ultrasound plus pulsed electromagnetic field improves recovery from peripheral arterial disease in hypertension. American journal of Transl Res. 2017; 9(9): 4184–4194.
The gene expression profiles in response to 102 traditional Chinese medicine (TCM) components: a general template for research on TCMs. Scientific Rep , 2017 , 7 (1) :352
Ginsenoside Rb1 protects against ischemia/reperfusion-induced myocardial injury via energy metabolism regulation mediated by RhoA signaling pathway. Scientific Reports, 2017
Design, synthesis and evaluation of novel angiotensin II receptor 1 antagonists with antihypertensive activities. RSC Advances, 2017
Bone marrow mesenchymal stem cells repair the hippocampal neurons and increase the expression of IGF‑1 after cardiac arrest in rats. Experimental & Therapeutic Medicine, 2017
Hypertonic saline infusion suppresses apoptosis of hippocampal cells in a rat model of cardiopulmonary resuscitation. Scientific Reports, 2017
Angiotensin I-converting enzyme inhibitory peptides from Sipuncula (Phascolosoma esculenta): Purification, identification, molecular docking and antihypertensive . Process Biochemistry 2017
Inhibition of soluble epoxide hydrolase lowers portal hypertension in cirrhotic rats by ameliorating endothelial dysfunction and liver fibrosis. Prostaglandins & ther lipid mediators 2017
Slowed relaxation of diaphragm in septic rats is associated with reduced expression of sarco‐endoplasmic reticulum CA2+‐ATPase genes SERCA1 and SERCA2. Muscle & nerve, 2016
Salvianolic acid B improves vascular endothelial function in diabetic rats with blood glucose fluctuations via suppression of endothelial cell apoptosis.European Journal of Pharmacology Volume 791, 15 November 2016, Pages 308-315
Characteristic Enhancement of Blood Pressure V-Shaped Waves in Sinoaortic-Denervated Rats in a Conscious and Quiet State. Physiological, 2016
Microarray expression profiling and gene ontology analysis of long non-coding RNAs in spontaneously hypertensive rats and their potential roles in the pathogenesis of hypertension. Molecular Medicine Reports, 2016
鬼针草水提物的降血压作用及其作用机制研究.广西医科大学学报,2017,34(02):177-180.
经胸右心室穿刺法测量大鼠右心室压力的研究.现代生物医学进展,2017,17(04):619-623.
丹参酮ⅡA对心肌缺血再灌注损伤大鼠氧化应激的保护作用.中国医药导报,2017,14(04):8-11.
红景天苷对实验性高血压大鼠血管功能的影响.中国中医基础医学杂志,2017,23(01):71-74.
炎性反应和交感神经系统在慢性心力衰竭大鼠中枢调控中的相互作用.解放军医药杂志,2017,29(01):31-34.
高血压小鼠心肌肥厚过程中心肌组织Prx-2、8-OHdG蛋白表达变化及意义.山东医药,2017,57(04):5-8.
参附注射液抗早、中期心源性休克大鼠微循环效应指标量效关系研究.中药新药与临床药理,2017,28(01):55-60
PI3K-mTOR信号通路对蛛网膜下腔出血大鼠海马区神经细胞自噬的调控作用.西安交通大学学报(医学版),2017,38(02):188-192.
Obestatin在心肌梗死后心力衰竭大鼠循环和肾脏的表达及其生物学意义.中国现代医学杂志,2017,27(01):6-10.
不同经穴针刺对自发性高血压大鼠降压效应的观察.广州中医药大学学报,2017,34(01):55-59.
自噬小体清除在七氟烷预处理延迟性心肌保护中的作用.中华急诊医学杂志,2017,26(01):65-70.
ERK信号通路抑制剂U0126对蛛网膜下腔出血大鼠早期脑损伤及神经元自噬的影响.西安交通大学学报(医学版),2017,38(01):18-23+28.
隔山香正丁醇部位对大鼠胸主动脉的舒张作用及机制的影响.中国实验方剂学杂志,2017,23(03):139-145.
络风宁1号方对心肌梗死大鼠血栓调节蛋白-活化蛋白C-内皮细胞蛋白C受体系统的调节作用.中国循证心血管医学杂志,2017,9(11):1342-1345.
N-乙酰半胱氨酸预防硝酸酯耐药的实验效果及机制探讨.中国循证心血管医学杂志,2017,9(11):1334-1337.
补肾养血明目方对ARPE-19细胞氧化损伤的保护机制研究.中国中医眼科杂志,2017,27(04):218-222
迷迭香提取物对大鼠心肌缺血再灌注损伤的保护作用.中国民族民间医药,2017,26(21):26-28+32.
龙灯胶囊对大鼠心肌缺血再灌注损伤的保护作用.中国民族民间医药,2017,26(21):29-32.
原花青素预处理对大鼠心肌缺血再灌注损伤的作用.中医学报,2017,32(11):2140-2143.
两种膜式氧合器对大鼠体外循环中动脉血氧分压及超敏肌钙蛋白的影响.贵州医药,2017,41(10):1011-1013.
短期快速失血对机体脂质过氧化水平影响的实验研究.临床输血与检验,2017,19(05):430-433.
δ受体在氢吗啡酮后处理维持大鼠离体心脏缺血再灌注时电生理稳定性中的作用.中华麻醉学杂志,2017,37(10):1208-1212.
电针内关穴预处理对心肌缺血再灌注损伤大鼠NO、NOS及线粒体膜电位的影响.上海针灸杂志,2017,36(10):1247-1252.
针刺“内关”预处理对大鼠缺血再灌注心肌的保护作用及机制研究.华中科技大学学报(医学版),2017,46(05):526-530.
大鼠离体肾脏灌流模型在筛选慢性肾病药物的初步应用.实验动物与比较医学,2017,37(05):357-362.

 

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